Good Laboratory Practice (GLP) principles are quality systems regarding the organisational processes and the conditions under non-clinical health and environmental safety studies are planned, carried out, controlled, registered, archived and reported.

They are used in the performance of tests to obtain data on the properties and hazards for people, animals and the environment of any chemical substance. The purpose of these tests is to submit the substances studied to the regulatory authorities responsible for their official registration as a preliminary step to marketing.

Thus, national GLP compliance programs were created to ensure that laboratories performing GLP comply with their principles. By the signing of mutual acceptance of data (MAD) agreements, they also ensure that the results of these tests are recognised by other EU and OECD Member States.

ENAC is the organisation designated by the competent Spanish government authorities as the control body for assessing and certifying GLP compliance in studies conducted with plant protection products, feed additives and industrial chemicals substances (including biocides), aromas and enzymes, new foods and technological coadjutants, thereby ensuring compliance with the European directives regulating this activity.